Is there a relationship between acne and diet?
Summary:
- Acne is a common skin condition that affects millions of people globally.
- Although acne mainly manifests itself through the appearance of pimples on the skin, its psychological effects are often underestimated.
- While genetics, hormones, and bacteria are the primary causes of acne, clinicians are still debating whether diet plays a role in acne outbreaks.
Since 1969, scientists have been investigating a possible link between chocolate and acne. Does blemish-free skin really require a chocolate-free diet?
Acne is the most common skin disease worldwide, affecting more than 85% of teenagers [1]. Acne can also affect adults, where two types of populations can be distinguished: people who developed acne during adolescence and might have persistent acne and those who develop it during adulthood, with a prevalence of women over men [2]. Although the manifestations of acne appear mainly on the skin, its effects can go much deeper, representing an emotional burden with a psychological impact on the patients. Indeed, acne represents a source of low self-esteem and embarrassment for many young adults, leading to anxiety, fear, anger and depression [3]. This is further exacerbated by misinformation and myths about acne onset and how it should be treated.
The aim of this article is to shed light on the causes of acne outbreaks and to dispel popular misconceptions about the disease. We will also discuss some scientific studies investigating the correlation between acne and diet.
Acne manifests itself mainly through the formation of pimples on the skin: our skin has pores and underlying glands which produce an oily substance called sebum. Sebum usually travels through follicles to reach the surface of the skin. However, when an excess of sebum is produced, the follicles can become plugged, resulting in a pimple. These plugs can get infected by Propionibacterium acnes, a bacterium that contributes to pimple infections [4]. Several factors can influence acne outbreak and its severity: genetics [5], stress [6], hormones [7], smoking [8], or excessive sweating. Hormonal changes occurring during adolescence and the menstrual cycle have an impact on sebum production by skin glands, and can therefore affect acne outbreaks [9]. Cosmetics and makeup were also shown to play a role in skin pore clogging [10]. Clinicians have also long suspected that diet plays a role in the development of this condition.
A recent study was conducted on 24’000 people reporting having acne at the time of the study, having had acne in the past, or with no history of acne [11]. The results showed a significant correlation between acne and the consumption of fatty and sugary products, sugar-sweetened beverages and milk, while no association was found with the consumption of meat, vegetables, fruit or dark chocolate. A plausible explanation would be that high-glycemic index foods can raise insulin blood levels which, as a result, would stimulate hormones that can increase sebum production and contribute to acne. In another study conducted on 47’000 female nurses, scientists found a positive correlation with some dairy foods (e.g. cream cheese, instant breakfast drink and cottage cheese), while no significant association was reported for French fries, chocolate candy, or pizza [12]. The association observed with some dairy products might be related to milk content, which is known to contain hormones that also increase sebum production. Accordingly, another study conducted on 65 participants showed no association between the consumption of chocolate bars with no milk component and acne [13]. The perceived correlation with commercial chocolate products may, therefore, be confounded by the presence of milk.
Even though research has made considerable progress in the last few years, there is still much debate about the correlation between acne and certain foods. Most of the studies are based on dietary records and can only detect correlation, but not causation, meaning that such studies cannot prove that specific dietary habits cause adult acne. Other factors called “confounders” contribute to the confusion regarding the correlation between diet and acne: people reporting having current acne and consuming more milk, might also live in areas with high levels of pollution, which introduces oxidative stress and can, therefore, damage the skin [14].
In conclusion, acne can affect both adolescents and adults and often represents an emotional burden for the patient. As a multifactorial disease, acne can have various causes and researchers are still investigating a possible contribution of diet to its onset. The studies investigating this specific aspect are survey research, and as such able to highlight correlation but not prove causation of specific food types and acne outbreaks. Importantly, every case should be addressed individually, and patients should rely on physicians to treat their condition.
References:
- Webster, G.F., Acne vulgaris. BMJ, 2002. 325(7362): p. 475-9.
- Skroza, N., et al., Adult Acne Versus Adolescent Acne: A Retrospective Study of 1,167 Patients. J Clin Aesthet Dermatol, 2018. 11(1): p. 21-25.
- Revol, O., N. Milliez, and D. Gerard, Psychological impact of acne on 21st-century adolescents: decoding for better care. Br J Dermatol, 2015. 172 Suppl 1: p. 52-8.
- Leyden, J.J., The evolving role of Propionibacterium acnes in acne. Semin Cutan Med Surg, 2001. 20(3): p. 139-43.
- Bataille, V., et al., The influence of genetics and environmental factors in the pathogenesis of acne: a twin study of acne in women. J Invest Dermatol, 2002. 119(6): p. 1317-22.
- Chiu, A., S.Y. Chon, and A.B. Kimball, The response of skin disease to stress: changes in the severity of acne vulgaris as affected by examination stress. Arch Dermatol, 2003. 139(7): p. 897-900.
- Ghosh, S., et al., Profiling and hormonal therapy for acne in women. Indian J Dermatol, 2014. 59(2): p. 107-15.
- Capitanio, B., et al., Acne and smoking. Dermatoendocrinol, 2009. 1(3): p. 129-35.
- Arora, M.K., A. Yadav, and V. Saini, Role of hormones in acne vulgaris. Clin Biochem, 2011. 44(13): p. 1035-1040.
- Suh, D.H., et al., Relationship between acne and the use of cosmetics: Results of a questionnaire study in 539 Korean individuals. J Cosmet Dermatol, 2021. 20(7): p. 2172-2178.
- Penso, L., et al., Association Between Adult Acne and Dietary Behaviors: Findings From the NutriNet-Santé Prospective Cohort Study. JAMA Dermatol, 2020. 156(8): p. 854-862.
- Adebamowo, C.A., et al., High school dietary dairy intake and teenage acne. J Am Acad Dermatol, 2005. 52(2): p. 207-14.
- Fulton, J.E., G. Plewig, and A.M. Kligman, Effect of chocolate on acne vulgaris. JAMA, 1969. 210(11): p. 2071-4.
- Puri, P., et al., Effects of air pollution on the skin: A review. Indian J Dermatol Venereol Leprol, 2017. 83(4): p. 415-423.