Transmission reduction tests in clinical trials, focus on the Pfizer COVID19 vaccine
Summary: Reduction of SARS-CoV-2 transmission is a major goal in the management of outbreaks and pandemics. Initial Pfizer/BioNTech clinical trials did not evaluate SARS-CoV-2 transmission but followed EMA’s recommendations. Clinical trials of vaccines do not usually study transmission. Instead, the reduction of infections is employed as a standard outcome. Recently, the lack of testing for the reduction of SARS-CoV-2 transmission […]